A game-changer for chronic

Wound
Treatment

Achieve total and faster wound healing with AUP-16, a topical cell therapy that accelerates healing of diabetic foot ulcers and other chronic, non-healing wounds.

Chronic and non-healing wound treatment is

Complex

Many available products can treat symptoms or target limited steps in the wound healing pathway: traditional or moist wound dressings, negative pressure wound therapy, cell and tissue based products, skin substitutes, growth factors.... Aurealis Therapeutics’ four-in-one topical treatment, AUP-16, accelerates healing by targeting multiple wound healing pathways and promoting tissue regeneration. Our unique technology overcomes the limitations of combining current treatments or combining existing therapeutic protein treatments, replacing them with a single therapeutic agent.

AUP-16:

One medicine has the benefits of four therapeutics

AUP-16 is a safe and effective recombinant live biotherapeutic product that features a patented active bacterial vector containing three therapeutic proteins (FGF2, IL4, and CSF1), produced continuously at the site of the wound, providing a combination biologic treatment in one product.

AUP for treatment of diabetic foot ulcer

This novel therapeutic is backed by pre-clinical and clinical results in wide-ranging applications like diabetic foot ulcers, other non-healing wounds, and inflammatory diseases. AUP-16 is made from live, food-grade bacteria and has the power to accelerate and provide complete wound healing, making future amputations unnecessary.

This remarkable advancement is ideal for patients who only achieve partial response to wound care dressings and treatment of symptoms. As opposed to the existing standard of care, AUP-16 promotes tissue regeneration in the wound to activate healing from within.

Highlights of AUP-16

Four-in-one

cell therapy stimulates
endogenous
tissue regeneration

Bioavailable

protein production
at the site of injury

Topical Application

makes it easy to
adminsiter

Safe

modified food-
grade bacteria

Learn more

About this
life-changing
technology

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News Feed

Aurealis Therapeutics Diabetic Foot Ulcer Dose Escalation Patient Trial Low Therapeutic Dose Cohort Completed Successfully, Advances to Medium Therapeutic Dose Group

Basel Switzerland, Kuopio Finland – May 27th, 2021.  Aurealis Therapeutics, a biopharmaceutical company developing its groundbreaking four-in-one technology -based product AUP-16, announced today that it has successfully completed the low therapeutic dose cohort in the diabetic foot ulcer (DFU) patient trial and has already enrolled and dosed the first patients in the medium therapeutic dose … Aurealis Therapeutics Diabetic Foot...

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Aurealis Therapeutics Novel Chronic Wound Treatment to be Presented at the 4th Experts Meeting on Microbiome & Skin Health and Disease on December 15th, 2020

Basel Switzerland, Kuopio Finland – December 15th, 2020. Haritha Samaranayake, MD, PhD, Medical Director of Aurealis Therapeutics will give a talk about development of AUP16, the company´s lead product for non-healing wounds such as diabetic foot ulcer. The presentation is titled “Development of a Live Biotherapeutic to treat diabetic foot ulcer“ and is scheduled for … Aurealis Therapeutics Novel Chronic...

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Aurealis Therapeutics Developing a Drug Therapy with Multiple Active Substances in One Product Has Initiated Repeated Dosing Groups in the Diabetic Foot Ulcer Patient Trial

Basel Switzerland, Kuopio Finland – November 17th, 2020. Aurealis Therapeutics, a private clinical-stage biopharmaceutical company, is making a difference in chronic, non-healing wounds by developing a therapy with multiple active substances in one product that are hitting all key pathomechanisms. Chronic wound care needs curative drugs with true active pharmaceutical substances, not just incrementally improved … Aurealis Therapeutics Developing a...

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